Catalase antibody (AA 1-225)

Catalog No. ABIN6137988

Product Details anti-Catalase Antibody

Target: Catalase (CAT)

Binding Specificity: AA 1-225

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Catalase antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Sequence: MADSRDPASD QMQHWKEQRA AQKADVLTTG AGNPVGDKLN VITVGPRGPL LVQDVVFTDE MAHFDRERIP ERVVHAKGAG AFGYFEVTHD ITKYSKAKVF EHIGKKTPIA VRFSTVAGES GSADTVRDPR GFAVKFYTED GNWDLVGNNT PIFFIRDPIL FPSFIHSQKR NPQTHLKDPD MVWDFWSLRP ESLHQVSFLF SDRGIPDGHR HMNGYGSHTF KLVNA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human Catalasealase (NP_001743.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000,IP,1:20 - 1:50

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Catalase

Target: Catalase (CAT)

Alternative Name: CAT (CAT Products)

Synonyms: 2210418N07 antibody, Cas-1 antibody, Cas1 antibody, Cs-1 antibody, CS1 antibody, Cat01 antibody, Catl antibody, fb68a12 antibody, wu:fb68a12 antibody, CAT antibody, CATA antibody, CG6871 antibody, CT21282 antibody, CatA antibody, DMCATHPO antibody, DROCATHPO antibody, Dmel\\CG6871 antibody, U00145 antibody, bs36h11.y1 antibody, cat antibody, GB11648 antibody, catalase antibody, Cat antibody, BA0843 antibody, DKFZp469E0232 antibody, catalase antibody, Catalase antibody, catalase, gene 2 antibody, CAT antibody, Cat antibody, cat antibody, cat.2 antibody, LOC769804 antibody, BA_0843 antibody

Background: This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.,CAT,catalase,MGC138422,MGC138424,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,Cardiac metabolism,CAT

Molecular Weight: 59 kDa

Gene ID: 847

UniProt: P04040

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism