CD4 antibody (AA 300-400)

Catalog No. ABIN6138187

The Rabbit Polyclonal anti-CD4 antibody has been validated for WB and IF. It is suitable to detect CD4 in samples from Human.

Quick Overview for CD4 antibody (AA 300-400) (ABIN6138187)

Target: CD4

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CD4 Antibody

Binding Specificity: AA 300-400

Sequence: ALEAKTGKLH QEVNLVVMRA TQLQKNLTCE VWGPTSPKLM LSLKLENKEA KVSKREKAVW VLNPEAGMWQ CLLSDSGQVL LESNIKVLPT WSTPVQPMAL I

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human CD4 (NP_000607.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.,CD4,CD4mut,Immunology & Inflammation,CD markers,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,CD4

Molecular Weight: 51 kDa

Gene ID: 920

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events