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E-cadherin antibody (AA 700-800)

Name: E-cadherin antibody (AA 700-800)
Brand: antibodies-online
SKU: ABIN6138279
Price: 877.74 USD
Availability: InStock

CDH1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Potential biological pathways affected by KLFs. (E-cadherin antibody (AA 700-800))

Immunofluorescence analysis of A-431 cells using E-Cadherin Rabbit pAb at dilution of 1:100 (40x lens). (E-cadherin antibody (AA 700-800))

Western blot analysis of extracts of various cell lines, using E-Cadherin antibody at 1:1000 dilution. (E-cadherin antibody (AA 700-800))

Immunofluorescence analysis of MCF7 cells using E-Cadherin Rabbit pAb at dilution of 1:100 (40x lens). (E-cadherin antibody (AA 700-800))

Immunohistochemistry of paraffin-embedded Rat kidney using E-Cadherin antibody at dilution of 1:50 (40x lens). (E-cadherin antibody (AA 700-800))

IHC

5 images

Catalog No. ABIN6138279

Datasheet as PDF

Target See all E-cadherin (CDH1) Antibodies

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
Binding Specificity
17

17

16

11

10

10

8

8

7

5

4

4

4

4

4

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 700-800
Reactivity
224

84

69

18

16

12

8

8

8

6

5

4

4

4

1

1

1

1

1

1
Human
Host
181

79

6

4

3
Rabbit
Compatible Secondaries
Clonality
165

100

4

4
Polyclonal
Conjugate
141

30

28

8

7

6

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This E-cadherin antibody is un-conjugated
Application
191

94

85

67

55

54

36

33

33

27

21

16

5

5

5

4

4

4

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence

PVEAGLQIPA ILGILGGILA LLILILLLLL FLRRRAVVKE PLLPPEDDTR DNVYYYDEEG GGEEDQDFDL SQLHRGLDAR PEVTRNDVAP TLMSVPRYLP R

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Purification

Affinity purification

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human E-Cadherin (NP_004351.1).

Isotype

IgG

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Application Notes

WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment

HIGH QUALITY

Restrictions

For Research Use only
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Target

E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))

Alternative Name

CDH1 (CDH1 Products)

Background

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.,Arc-1,CD324,CDHE,ECAD,LCAM,UVO,CDH1,E-Cadherin,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,CD markers,Neuroscience,Calcium Signaling,CDH1

Molecular Weight

90 kDa/97 kDa

Gene ID

999

UniProt

P12830

Pathways

WNT Signaling, Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation