Cholesterol Esterase antibody (AA 350-550)

Catalog No. ABIN6138393

This anti-Cholesterol Esterase antibody is a Rabbit Polyclonal antibody detecting Cholesterol Esterase in WB. Suitable for Human.

Quick Overview for Cholesterol Esterase antibody (AA 350-550) (ABIN6138393)

Target: Cholesterol Esterase (CEL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cholesterol Esterase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cholesterol Esterase Antibody

Binding Specificity: AA 350-550

Sequence: IDMPAINKGN KKVTEEDFYK LVSEFTITKG LRGAKTTFDV YTESWAQDPS QENKKKTVVD FETDVLFLVP TEIALAQHRA NAKSAKTYAY LFSHPSRMPV YPKWVGADHA DDIQYVFGKP FATPTGYRPQ DRTVSKAMIA YWTNFAKTGD PNMGDSAVPT HWEPYTTENS GYLEITKKMG SSSMKRSLRT NFLRYWTLTY L

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CEL (NP_001798.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cholesterol Esterase

Target: Cholesterol Esterase (CEL)

Alternative Name: CEL

Background: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.,CEL,BAL,BSDL,BSSL,CELL,CEase,FAP,FAPP,LIPA,MODY8,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,Lipid Metabolism,CEL

Molecular Weight: 71 kDa/79 kDa

Gene ID: 1056

UniProt: P19835

Pathways: Lipid Metabolism