Choline Acetyltransferase antibody (AA 331-630)

Catalog No. ABIN6138488

The Rabbit Polyclonal anti-Choline Acetyltransferase antibody is suitable to detect Choline Acetyltransferase in samples from Human. It has been validated for WB, IHC and IF.

Quick Overview for Choline Acetyltransferase antibody (AA 331-630) (ABIN6138488)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Choline Acetyltransferase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Choline Acetyltransferase Antibody

Binding Specificity: AA 331-630

Sequence: VLVQCTEHLL KHMTQSSRKL IRADSVSELP APRRLRWKCS PEIQGHLASS AEKLQRIVKN LDFIVYKFDN YGKTFIKKQK CSPDAFIQVA LQLAFYRLHR RLVPTYESAS IRRFQEGRVD NIRSATPEAL AFVRAVTDHK AAVPASEKLL LLKDAIRAQT AYTVMAITGM AIDNHLLALR ELARAMCKEL PEMFMDETYL MSNRFVLSTS QVPTTTEMFC CYGPVVPNGY GACYNPQPET ILFCISSFHS CKETSSSKFA KAVEESLIDM RDLCSLLPPT ESKPLATKEK ATRPSQGHQP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 331-630 of human CHAT (NP_001136401.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Alternative Name: CHAT

Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.,CHAT,CHOACTASE,CMS1A,CMS1A2,CMS6,Neuroscience,Cell Type Marker,Neuron marker,CHAT

Molecular Weight: 70 kDa/74 kDa/82 kDa

Gene ID: 1103

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development