C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 22-196) antibody

Catalog No. ABIN6138705

The Rabbit Polyclonal anti-C-Type Lectin Domain Family 1, Member B antibody is suitable to detect C-Type Lectin Domain Family 1, Member B in samples from Human. It has been validated for WB.

Quick Overview for C-Type Lectin Domain Family 1, Member B (CLEC1B) (AA 22-196) antibody (ABIN6138705)

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: AA 22-196

Sequence: AVMQRNYLQG ENENRTGTLQ QLAKRFCQYV VKQSELKGTF KGHKCSPCDT NWRYYGDSCY GFFRHNLTWE ESKQYCTDMN ATLLKIDNRN IVEYIKARTH LIRWVGLSRQ KSNEVWKWED GSVISENMFE FLEDGKGNMN CAYFHNGKMH PTFCENKHYL MCERKAGMTK VDQLP

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-196 of human CLEC1B (NP_001092901.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: C-Type Lectin Domain Family 1, Member B (CLEC1B)

Alternative Name: CLEC1B

Background: Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1, MIM 602894) and NKG2D (KLRC4, MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011],CLEC1B,1810061I13Rik,CLEC2,CLEC2B,PRO1384,QDED721,Immunology & Inflammation,CLEC1B

Molecular Weight: 23 kDa/26 kDa

Gene ID: 51266

UniProt: Q9P126