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Diazepam Binding Inhibitor antibody (AA 1-114)

DBI Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6139420
  • Target See all Diazepam Binding Inhibitor (DBI) Antibodies
    Diazepam Binding Inhibitor (DBI)
    Binding Specificity
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-114
    Reactivity
    • 34
    • 13
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 2
    Rabbit
    Clonality
    • 38
    • 1
    Polyclonal
    Conjugate
    • 20
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Diazepam Binding Inhibitor antibody is un-conjugated
    Application
    • 28
    • 16
    • 16
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequence
    MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK QATVGDINTE RPGMLDFTGK AKWDAWNELK GTSKEDAMKA YINKVEELKK KYGI
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-114 of human DBI (NP_001171513.1).
    Isotype
    IgG
    Top Product
    Discover our top product DBI Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Diazepam Binding Inhibitor (DBI)
    Alternative Name
    DBI (DBI Products)
    Synonyms
    ACBD1 antibody, ACBP antibody, CCK-RP antibody, EP antibody, dbib antibody, DBI antibody, wu:fb63e10 antibody, zgc:56108 antibody, zgc:77734 antibody, Acbp antibody, endozepine antibody, Acoabp3 antibody, Ep antibody, Odn antibody, RNACOABP3 antibody, Ttn antibody, acbd1 antibody, acbp antibody, cck-rp antibody, dbi antibody, dbi-a antibody, dbi-b antibody, dbia antibody, diazepam binding inhibitor, acyl-CoA binding protein antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antibody, diazepam-binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antibody, acyl-CoA-binding protein antibody, diazepam binding inhibitor antibody, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antibody, DBI antibody, dbi.S antibody, dbi antibody, LOC706367 antibody, Dbi antibody, dbi.L antibody
    Background
    This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.,DBI,ACBD1,ACBP,CCK-RP,EP,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DBI
    Molecular Weight
    10 kDa/11 kDa/13 kDa/14 kDa/16 kDa
    Gene ID
    1622
    UniProt
    P07108
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