DPPA4 antibody

Catalog No. ABIN7228284

The Rabbit Polyclonal anti-DPPA4 antibody (ABIN7228284) specifically detects DPPA4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DPPA4 antibody (ABIN7228284)

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPPA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DPPA4 Antibody

Purpose: Rabbit Anti-DPPA4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DPPA4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DPPA4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DPPA4

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Alternative Name: DPPA4

Background: Developmental pluripotency-associated protein 4DPPA4 encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18. but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of DPPA4 have been identified. Alternative splicing results in multiple transcript variants.

Molecular Weight: 33kD

Gene ID: 55211

UniProt: Q7L190