EPM2A antibody (AA 244-331)

Catalog No. ABIN6140229

The Rabbit Polyclonal anti-EPM2A antibody (ABIN6140229) specifically detects EPM2A in WB. The antibody is reactive with Human samples.

Quick Overview for EPM2A antibody (AA 244-331) (ABIN6140229)

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPM2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPM2A Antibody

Binding Specificity: AA 244-331

Sequence: MLPQAVCLLH ALLEKGHIVY VHCNAGVGRS TAAVCGWLQY VMGWNLRKVQ YFLMAKRPAV YIDEEALARA QEDFFQKFGK VRSSVCSL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 244-331 of human EPM2A (NP_005661.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPM2A

Target: EPM2A (Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Alternative Name: EPM2A

Background: This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.,EPM2A,EPM2,MELF,laforin,Signal Transduction,Endocrine & Metabolism,EPM2A

Molecular Weight: 9 kDa/15 kDa/20 kDa/22 kDa/24 kDa/35 kDa/37 kDa

Gene ID: 7957

UniProt: O95278

Pathways: Cellular Glucan Metabolic Process