ERBB2IP antibody (AA 1152-1371)

Catalog No. ABIN6140250

This Rabbit Polyclonal antibody specifically detects ERBB2IP in WB. It exhibits reactivity toward Human.

Quick Overview for ERBB2IP antibody (AA 1152-1371) (ABIN6140250)

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB2IP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ERBB2IP Antibody

Binding Specificity: AA 1152-1371

Sequence: IPERTMSVSD FNYSRTSPSK RPNARVGSEH SLLDPPGKSK VPRDWREQVL RHIEAKKLEK MPLSNGQMGQ PLRPQANYSQ IHHPPQASVA RHPSREQLID YLMLKVAHQP PYTQPHCSPR QGHELAKQEI RVRVEKDPEL GFSISGGVGG RGNPFRPDDD GIFVTRVQPE GPASKLLQPG DKIIQANGYS FINIEHGQAV SLLKTFQNTV ELIIVREVSS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERBB2IP

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Alternative Name: ERBB2IP

Background: This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ERBIN,ERBB2IP,HEL-S-78,LAP2,erbin,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,Cytokines,ERBB2IP

Molecular Weight: 146-159 kDa

Gene ID: 55914

UniProt: Q96RT1

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization