ERBB2IP antibody (N-Term)

Catalog No. ABIN966084

The Rabbit Polyclonal anti-ERBB2IP antibody (ABIN966084) specifically detects ERBB2IP in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for ERBB2IP antibody (N-Term) (ABIN966084)

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERBB2IP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ERBB2IP Antibody

Binding Specificity: N-Term

Purification: Purified by antigen-specific affinity chromatography.

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ERBB2IP (Erbb2-interacting protein)

Application Details

Application Notes: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for ERBB2IP

Target: ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))

Alternative Name: ERBB2IP

Background: ERBB2IP (Erbb2-interacting protein) acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated Tyr-1248 of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. ERBB2IP (Erbb2-interacting protein) interacts with ERBB2, BPAG1 and ITGB4. It may favor the localization of ERBB2, by restricting its presence to the basolateral membrane of epithelial cells. ERBB2IP is also found to interact with ARVCF and delta catenin.

Pathways: EGFR Signaling Pathway, Asymmetric Protein Localization