ERBB2IP antibody
Quick Overview for ERBB2IP antibody (ABIN7073858)
Target
See all ERBB2IP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Erbin
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Application Notes
- WB (H,M,R) 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- ERBB2IP (Erbb2 Interacting Protein (ERBB2IP))
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Alternative Name
- Erbin
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Background
- The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Molecular Weight
- 157 kDa
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Gene ID
- 59079
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NCBI Accession
- NP_001005868
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UniProt
- Q80TH2
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Pathways
- EGFR Signaling Pathway, Asymmetric Protein Localization
Target
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