GABPA antibody (AA 1-100)

Catalog No. ABIN6140887

Cited in 3+ publications. The Rabbit Polyclonal anti-GABPA antibody (ABIN6140887) specifically detects GABPA in WB. The antibody is reactive with Human samples.

Quick Overview for GABPA antibody (AA 1-100) (ABIN6140887)

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABPA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABPA Antibody

Binding Specificity: AA 1-100

Sequence: MTKREAEELI EIEIDGTEKA ECTEESIVEQ TYAPAECVSQ AIDINEPIGN LKKLLEPRLQ CSLDAHEICL QDIQLDPERS LFDQGVKTDG TVQLSVQVIS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GABPA (NP_002031.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-GABPA antibody (ABIN6140887)

Zhao, Tao, Qi, Xu, Yin, Peng: "Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress." in: Redox biology, Vol. 16, pp. 189-198, (2018) (PubMed).

Chen, Jiang, Li, Bai, Zhao, Zhang, Zhang: "Hydrogen protects against liver injury during CO2 pneumoperitoneum in rats." in: Oncotarget, Vol. 9, Issue 2, pp. 2631-2645, (2018) (PubMed).

Khaliq, Jing, Ke, Ke-Li, Peng-Peng, Cui, Wei-Wei, Zhixin, Hua-Zhen, Hui, Ju-Ming, Ke-Mei: "Boron Affects the Development of the Kidney Through Modulation of Apoptosis, Antioxidant Capacity, and Nrf2 Pathway in the African Ostrich Chicks." in: Biological trace element research, Vol. 186, Issue 1, pp. 226-237, (2018) (PubMed).

Target Details for GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Alternative Name: GABPA

Background: This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.,GABPA,E4TF1-60,E4TF1A,NFT2,NRF2,NRF2A,RCH04A07,Epigenetics & Nuclear Signaling,Transcription Factors,GABPA

Molecular Weight: 51 kDa

Gene ID: 2551

UniProt: Q06546

Pathways: Myometrial Relaxation and Contraction