GLA antibody (AA 150-429)

Catalog No. ABIN6141113

The Rabbit Polyclonal anti-GLA antibody (ABIN6141113) specifically detects GLA in WB. The antibody is reactive with Human samples.

Quick Overview for GLA antibody (AA 150-429) (ABIN6141113)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLA Antibody

Binding Specificity: AA 150-429

Sequence: GYYDIDAQTF ADWGVDLLKF DGCYCDSLEN LADGYKHMSL ALNRTGRSIV YSCEWPLYMW PFQKPNYTEI RQYCNHWRNF ADIDDSWKSI KSILDWTSFN QERIVDVAGP GGWNDPDMLV IGNFGLSWNQ QVTQMALWAI MAAPLFMSND LRHISPQAKA LLQDKDVIAI NQDPLGKQGY QLRQGDNFEV WERPLSGLAW AVAMINRQEI GGPRSYTIAV ASLGKGVACN PACFITQLLP VKRKLGFYEW TSRLRSHINP TGTVLLQLEN TMQMSLKDLL

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-429 of human Galactosidase alpha (Galactosidase alpha (GLA)) (NP_000160.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: GLA

Background: This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.,GLA,GALA,Cardiovascular,Blood,Blood Cell Antigens,GLA

Molecular Weight: 48 kDa

Gene ID: 2717

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome