Gephyrin antibody (AA 520-769)

Catalog No. ABIN6141324

The Rabbit Polyclonal anti-Gephyrin antibody has been validated for WB. It is suitable to detect Gephyrin in samples from Human.

Quick Overview for Gephyrin antibody (AA 520-769) (ABIN6141324)

Target: Gephyrin (GPHN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Gephyrin Antibody

Binding Specificity: AA 520-769

Sequence: TVGVTEVEVN KFPVVAVMST GNELLNPEDD LLPGKIRDSN RSTLLATIQE HGYPTINLGI VGDNPDDLLN ALNEGISRAD VIITSGGVSM GEKDYLKQVL DIDLHAQIHF GRVFMKPGLP TTFATLDIDG VRKIIFALPG NPVSAVVTCN LFVVPALRKM QGILDPRPTI IKARLSCDVK LDPRPEYHRC ILTWHHQEPL PWAQSTGNQM SSRLMSMRSA NGLLMLPPKT EQYVELHKGE VVDVMVIGRL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 520-769 of human Gephyrin (NP_065857.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: GPHN

Background: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.,GPHN,GEPH,GPH,GPHRYN,HKPX1,MOCODC,gephyrin,Cell Biology & Developmental Biology,Cell Adhesion,Microtubules,Neuroscience,GPHN

Molecular Weight: 79 kDa/83 kDa

Gene ID: 10243

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development