ITGB1 antibody (AA 600-700)

Catalog No. ABIN6142578

This Rabbit Polyclonal antibody specifically detects ITGB1 in WB and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for ITGB1 antibody (AA 600-700) (ABIN6142578)

Target: ITGB1 (Integrin beta 1 (ITGB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-ITGB1 Antibody

Binding Specificity: AA 600-700

Sequence: EASNGQICNG RGICECGVCK CTDPKFQGQT CEMCQTCLGV CAEHKECVQC RAFNKGEKKD TCTQECSYFN ITKVESRDKL PQPVQPDPVS HCKEKDVDDC W

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human Integrin-beta1/CD29 (NP_391988.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-ITGB1 antibody (ABIN6142578)

Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

Target Details for ITGB1

Target: ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name: ITGB1

Background: Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.,CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB,Integrin beta 1,ITGB1,Integrin β1,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Neuroscience,Cell Type Marker,Stem Cells,Embryonic Stem Cells,Mesenchymal Stem Cells,Neural Stem Cell marker,ITGB1

Molecular Weight: 87 kDa/88 kDa/91 kDa

Gene ID: 3688

UniProt: P05556

Pathways: Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome