KIT antibody (AA 25-295)

Catalog No. ABIN6142896

The Rabbit Polyclonal anti-KIT antibody has been validated for WB, IHC and IF. It is suitable to detect KIT in samples from Human.

Quick Overview for KIT antibody (AA 25-295) (ABIN6142896)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-KIT Antibody

Binding Specificity: AA 25-295

Sequence: SQPSVSPGEP SPPSIHPGKS DLIVRVGDEI RLLCTDPGFV KWTFEILDET NENKQNEWIT EKAEATNTGK YTCTNKHGLS NSIYVFVRDP AKLFLVDRSL YGKEDNDTLV RCPLTDPEVT NYSLKGCQGK PLPKDLRFIP DPKAGIMIKS VKRAYHRLCL HCSVDQEGKS VLSEKFILKV RPAFKAVPVV SVSKASYLLR EGEEFTVTCT IKDVSSSVYS TWKRENSQTK LQEKYNSWHH GDFNYERQAT LTISSARVND SGVFMCYANN T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human CD117/c-Kit (NP_000213.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: KIT

Background: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.,KIT,C-Kit,CD117,PBT,SCFR,c-kit,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Cytokines,Neuroscience,Cell Type Marker,Stem Cells,Germline Stem Cells,Hematopoietic Progenitors,KIT

Molecular Weight: 46 kDa/109 kDa

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity