Kallikrein 6 antibody (C-Term)

Catalog No. ABIN6142958

The Rabbit Polyclonal anti-Kallikrein 6 antibody has been validated for WB. It is suitable to detect Kallikrein 6 in samples from Human.

Quick Overview for Kallikrein 6 antibody (C-Term) (ABIN6142958)

Target: Kallikrein 6 (KLK6)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Kallikrein 6 Antibody

Binding Specificity: C-Term

Sequence: AASHDQDIML LRLARPAKLS ELIQPLPLER DCSANTTSCH ILGWGKTADG DFPDTIQCAY IHLVSREECE HAYPGQITQN MLCAGDEKYG KDSCQGDSGG PLVCGDHLRG LVSWGNIPCG SKEKPGVYTN VCRYTNWIQK TIQAK

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human KLK6 (NP_002765.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Kallikrein 6

Target: Kallikrein 6 (KLK6)

Alternative Name: KLK6

Background: This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,KLK6,Bssp,Klk7,PRSS18,PRSS9,SP59,hK6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,KLK6

Molecular Weight: 4 kDa/15 kDa/26 kDa

Gene ID: 5653

UniProt: Q92876

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling