KRT81 antibody (AA 240-390)

Catalog No. ABIN6143041

This Rabbit Polyclonal antibody specifically detects KRT81 in WB. It exhibits reactivity toward Human.

Quick Overview for KRT81 antibody (AA 240-390) (ABIN6143041)

Target: KRT81 (Keratin 81 (KRT81))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT81 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRT81 Antibody

Binding Specificity: AA 240-390

Sequence: RRLYEEEILI LQSHISDTSV VVKLDNSRDL NMDCIIAEIK AQYDDIVTRS RAEAESWYRS KCEEMKATVI RHGETLRRTK EEINELNRMI QRLTAEVENA KCQNSKLEAA VAQSEQQGEA ALSDARCKLA ELEGALQKAK QDMACLIREY Q

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-390 of human KRT81 (NP_002272.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KRT81

Target: KRT81 (Keratin 81 (KRT81))

Alternative Name: KRT81

Background: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.,KRT81,HB1,Hb-1,KRTHB1,MLN137,ghHkb1,hHAKB2-1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Keratin,KRT81

Molecular Weight: 54 kDa

Gene ID: 3887

UniProt: Q14533