KRT81 antibody (AA 40-120)
Quick Overview for KRT81 antibody (AA 40-120) (ABIN7229328)
Target
See all KRT81 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-120
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Purpose
- Rabbit Anti-KRT81 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of KRT81 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human KRT81 protein at AA range: 40-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- KRT81 (Keratin 81 (KRT81))
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Alternative Name
- KRT81
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Background
- Keratin, type II cuticular Hb1, Hair keratin K2.9, Keratin, hair, basic, 1, Keratin-81, K81, Metastatic lymph node 137 gene protein, MLN 137, Type II hair keratin Hb1, Type-II keratin Kb21, ghHKb1, ghHb1KRT81 (Keratin 81) is a Protein Coding gene. Diseases associated with KRT81 include Monilethrix and Hair Disease. Among its related pathways are Keratinization and Developmental Biology. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in KRT81 and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
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Molecular Weight
- 55kD
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Gene ID
- 3887
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UniProt
- Q14533
Target
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