LRP8 antibody (C-Term)

Catalog No. ABIN6143337

This Rabbit Polyclonal antibody specifically detects LRP8 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for LRP8 antibody (C-Term) (ABIN6143337)

Target: LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRP8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LRP8 Antibody

Binding Specificity: C-Term

Sequence: PLWAEPCLGE TREPEDPAPA LKELFVLPGE PRSQLHQLPK NPLSELPVVK SKRVALSLED DGLP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human ApoER2/ApoER2/LRP8 (NP_004622.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LRP8

Target: LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))

Alternative Name: LRP8

Background: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,LRP8,APOER2,HSZ75190,LRP-8,MCI1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,LRP8

Molecular Weight: 77 kDa/87 kDa/99 kDa/105 kDa

Gene ID: 7804

UniProt: Q14114