LRP8 antibody (AA 42-182)

Catalog No. ABIN7193275

This Mouse Monoclonal antibody specifically detects LRP8 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for LRP8 antibody (AA 42-182) (ABIN7193275)

Target: LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP8 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 7G12E2

Product Details anti-LRP8 Antibody

Binding Specificity: AA 42-182

Purpose: LRP8 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human LRP8 (AA: 42-182) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for LRP8

Target: LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))

Alternative Name: LRP8

Background:

This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 105.6 kDa

UniProt: Q14114