MDFI antibody (AA 1-160)

Catalog No. ABIN6143663

This Rabbit Polyclonal antibody specifically detects MDFI in WB and IF. It exhibits reactivity toward Human.

Quick Overview for MDFI antibody (AA 1-160) (ABIN6143663)

Target: MDFI (MyoD Family Inhibitor (MDFI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MDFI antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MDFI Antibody

Binding Specificity: AA 1-160

Sequence: MYQVSGQRPS GCDAPYGAPS AAPGPAQTLS LLPGLEVVTG STHPAEAAPE EGSLEEAATP MPQGNGPGIP QGLDSTDLDV PTEAVTCQPQ GNPLGCTPLL PNDSGHPSEL GGTRRAGNGA LGGPKAHRKL QTHPSLASQG SKKSKSSSKS TTSQIPLQAQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MDFI (NP_005577.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MDFI

Target: MDFI (MyoD Family Inhibitor (MDFI))

Alternative Name: MDFI

Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.,MDFI,I-MF,I-mfa,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,MDFI

Molecular Weight: 25 kDa

Gene ID: 4188

UniProt: Q99750

Pathways: Maintenance of Protein Location