MIB1 antibody (AA 560-860)

Catalog No. ABIN6143827

The Rabbit Polyclonal anti-MIB1 antibody has been validated for WB and IHC. It is suitable to detect MIB1 in samples from Human.

Quick Overview for MIB1 antibody (AA 560-860) (ABIN6143827)

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MIB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MIB1 Antibody

Binding Specificity: AA 560-860

Sequence: DSEGDTPLHD AISKKRDDIL AVLLEAGADV TITNNNGFNA LHHAALRGNP SAMRVLLSKL PRPWIVDEKK DDGYTALHLA ALNNHVEVAE LLVHQGNANL DIQNVNQQTA LHLAVERQHT QIVRLLVRAG AKLDIQDKDG DTPLHEALRH HTLSQLRQLQ DMQDVGKVDA AWEPSKNTLI MGLGTQGAEK KSAASIACFL AANGADLSIR NKKGQSPLDL CPDPNLCKAL AKCHKEKVSG QVGSRSPSMI SNDSETLEEC MVCSDMKRDT LFGPCGHIAT CSLCSPRVKK CLICKEQVQS R

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-860 of human MIB1/DIP1 (NP_065825.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MIB1

Target: MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))

Alternative Name: MIB1

Background: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).,MIB1,DIP-1,DIP1,LVNC7,MIB,ZZANK2,ZZZ6,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Stem Cells,MIB1

Molecular Weight: 110 kDa

Gene ID: 57534

UniProt: Q86YT6

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection