MYL12A antibody (AA 92-171)

Catalog No. ABIN6144243

This anti-MYL12A antibody is a Rabbit Polyclonal antibody detecting MYL12A in WB. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for MYL12A antibody (AA 92-171) (ABIN6144243)

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYL12A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MYL12A Antibody

Binding Specificity: AA 92-171

Sequence: KLNGTDPEDV IRNAFACFDE EATGTIQEDY LRELLTTMGD RFTDEEVDEL YREAPIDKKG NFNYIEFTRI LKHGAKDKDD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 92-171 of human MYL12A (NP_006462.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-MYL12A antibody (ABIN6144243)

Niu, Pi, Baral, Xia, He, Li, Jin, Li, Wang, Mao, Hu: "P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 3, pp. 515-524, (2017) (PubMed).

Target Details for MYL12A

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Alternative Name: MYL12A

Background: This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.,MYL12A,HEL-S-24,MLC-2B,MLCB,MRCL3,MRLC3,MYL2B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,MYL12A

Molecular Weight: 19 kDa

Gene ID: 10627

UniProt: P19105