NDE1 antibody (AA 1-110)

Catalog No. ABIN6144443

This anti-NDE1 antibody is a Rabbit Polyclonal antibody detecting NDE1 in WB and IHC. Suitable for Human.

Quick Overview for NDE1 antibody (AA 1-110) (ABIN6144443)

Target: NDE1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NDE1 Antibody

Binding Specificity: AA 1-110

Sequence: MEDSGKTFSS EEEEANYWKD LAMTYKQRAE NTQEELREFQ EGSREYEAEL ETQLQQIETR NRDLLSENNR LRMELETIKE KFEVQHSEGY RQISALEDDL AQTKAIKDQL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human NDE1 (NP_060138.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.,NDE1,HOM-TES-87,LIS4,MHAC,NDE,NUDE,NUDE1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Neuroscience,NDE1

Molecular Weight: 37 kDa/38 kDa

Gene ID: 54820

UniProt: Q9NXR1