P2RY2 antibody (AA 278-377)
Quick Overview for P2RY2 antibody (AA 278-377) (ABIN6145129)
Target
See all P2RY2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 278-377
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Sequence
- CHTLNAINMA YKVTRPLASA NSCLDPVLYF LAGQRLVRFA RDAKPPTGPS PATPARRRLG LRRSDRTDMQ RIEDVLGSSE DSRRTESTPA GSENTKDIRL
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))
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Alternative Name
- P2RY2
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Background
- The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.,P2RY2,HP2U,P2RU1,P2U,P2U1,P2UR,P2Y2,P2Y2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,P2RY2
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Molecular Weight
- 42 kDa
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Gene ID
- 5029
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UniProt
- P41231
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Smooth Muscle Cell Migration
Target
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