PAK4 antibody (AA 120-280)

Catalog No. ABIN6145188

This anti-PAK4 antibody is a Rabbit Polyclonal antibody detecting PAK4 in WB and IF. Suitable for Human.

Quick Overview for PAK4 antibody (AA 120-280) (ABIN6145188)

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PAK4 Antibody

Binding Specificity: AA 120-280

Sequence: EPATTARGGP GKAGSRGRFA GHSEAGGGSG DRRRAGPEKR PKSSREGSGG PQESSRDKRP LSGPDVGTPQ PAGLASGAKL AAGRPFNTYP RADTDHPSRG AQGEPHDVAP NGPSAGGLAI PQSSSSSSRP PTRARGAPSP GVLGPHASEP QLAPPACTPA A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human PAK4 (NP_001014831.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAK4

Target: PAK4 (P21-Activated Kinase 4 (PAK4))

Alternative Name: PAK4

Background: PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,PAK4,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cytoskeleton,Microfilaments,TGF-b-Smad Signaling Pathway,PAK4

Molecular Weight: 47 kDa/48 kDa/54 kDa/64 kDa

Gene ID: 10298

UniProt: O96013

Pathways: RTK Signaling