PHIP antibody (AA 1542-1821)

Catalog No. ABIN6145556

This Rabbit Polyclonal antibody specifically detects PHIP in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PHIP antibody (AA 1542-1821) (ABIN6145556)

Target: PHIP (Pleckstrin Homology Domain Interacting Protein (PHIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PHIP Antibody

Binding Specificity: AA 1542-1821

Sequence: KTILENSVKH SKALNTLSSP GQSSFSHGTR NNSAKENMEK EKPVKRKMKS SVLPKASTLS KSSAVIEQGD CKNNALVPGT IQVNGHGGQP SKLVKRGPGR KPKVEVNTNS GEIIHKKRGR KPKKLQYAKP EDLEQNNVHP IRDEVLPSST CNFLSETNNV KEDLLQKKNR GGRKPKRKMK TQKLDADLLV PASVKVLRRS NRKKIDDPID EEEEFEELKG SEPHMRTRNQ GRRTAFYNED DSEEEQRQLL FEDTSLTFGT SSRGRVRKLT EKAKANLIGW

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1542-1821 of human PHIP (NP_060404.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHIP

Target: PHIP (Pleckstrin Homology Domain Interacting Protein (PHIP))

Alternative Name: PHIP

Background: This gene encodes a protein that binds to the insulin receptor substrate 1 protein and regulates glucose transporter translocation in skeletal muscle cells. The encoded protein may also regulate growth and survival of pancreatic beta cells. Elevated copy number of this gene may be associated with melanoma severity and the encoded protein may promote melanoma metastasis in human patients.,PHIP,BRWD2,DCAF14,WDR11,ndrp,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,PHIP

Molecular Weight: 206 kDa

Gene ID: 55023

UniProt: Q8WWQ0

Pathways: Protein targeting to Nucleus