PNMT antibody (AA 1-282)

Catalog No. ABIN6145848

This Rabbit Polyclonal antibody specifically detects PNMT in WB. It exhibits reactivity toward Human.

Quick Overview for PNMT antibody (AA 1-282) (ABIN6145848)

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PNMT Antibody

Binding Specificity: AA 1-282

Sequence: MSGADRSPNA GAAPDSAPGQ AAVASAYQRF EPRAYLRNNY APPRGDLCNP NGVGPWKLRC LAQTFATGEV SGRTLIDIGS GPTVYQLLSA CSHFEDITMT DFLEVNRQEL GRWLQEEPGA FNWSMYSQHA CLIEGKGECW QDKERQLRAR VKRVLPIDVH QPQPLGAGSP APLPADALVS AFCLEAVSPD LASFQRALDH ITTLLRPGGH LLLIGALEES WYLAGEARLT VVPVSEEEVR EALVRSGYKV RDLRTYIMPA HLQTGVDDVK GVFFAWAQKV GL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human PNMT (NP_002677.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PNMT

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Alternative Name: PNMT

Background: The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.,PNMT,PENT,PNMTase,Cancer,Endocrine & Metabolism,Neuroscience,Cardiovascular,PNMT

Molecular Weight: 30 kDa

Gene ID: 5409

UniProt: P11086

Pathways: Response to Water Deprivation