PTPRN antibody (AA 600-889)
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- Target See all PTPRN Antibodies
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
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Binding Specificity
- AA 600-889
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPRN antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- STGHMILAYM EDHLRNRDRL AKEWQALCAY QAEPNTCATA QGEGNIKKNR HPDFLPYDHA RIKLKVESSP SRSDYINASP IIEHDPRMPA YIATQGPLSH TIADFWQMVW ESGCTVIVML TPLVEDGVKQ CDRYWPDEGA SLYHVYEVNL VSEHIWCEDF LVRSFYLKNV QTQETRTLTQ FHFLSWPAEG TPASTRPLLD FRRKVNKCYR GRSCPIIVHC SDGAGRTGTY ILIDMVLNRM AKGVKEIDIA ATLEHVRDQR PGLVRSKDQF EFALTAVAEE VNAILKALPQ
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 600-889 of human PTPRN (NP_001186693.1).
- Isotype
- IgG
- Top Product
- Discover our top product PTPRN Primary Antibody
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
- Alternative Name
- PTPRN (PTPRN Products)
- Synonyms
- IA-2 antibody, IA-2/PTP antibody, IA2 antibody, ICA512 antibody, R-PTP-N antibody, mIA-A antibody, mKIAA4064 antibody, Ia-2 antibody, fc43c04 antibody, ptprn antibody, wu:fc43c04 antibody, ia-2 antibody, ia2 antibody, ica512 antibody, r-ptp-n antibody, protein tyrosine phosphatase, receptor type N antibody, protein tyrosine phosphatase, receptor type, N antibody, protein tyrosine phosphatase, receptor type, Na antibody, protein tyrosine phosphatase, receptor type N L homeolog antibody, PTPRN antibody, Ptprn antibody, ptprna antibody, ptprn.L antibody
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.,PTPRN,IA-2,IA-2/PTP,IA2,ICA512,R-PTP-N,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,PTPRN
- Molecular Weight
- 96 kDa/102 kDa/105 kDa
- Gene ID
- 5798
- UniProt
- Q16849
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