PTPRN antibody

Catalog No. ABIN7251919

The Rabbit Polyclonal anti-PTPRN antibody is suitable to detect PTPRN in samples from Human, Rat and Mouse. It has been validated for ELISA and IHC.

Quick Overview for PTPRN antibody (ABIN7251919)

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRN antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PTPRN Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PTPRN

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRN

Target: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Alternative Name: PTPRN

Background: IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.

UniProt: Q16849