RACGAP1 antibody (AA 353-632)

Catalog No. ABIN6146621

This Rabbit Polyclonal antibody specifically detects RACGAP1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for RACGAP1 antibody (AA 353-632) (ABIN6146621)

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RACGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RACGAP1 Antibody

Binding Specificity: AA 353-632

Sequence: DFVSQTSPMI PSIVVHCVNE IEQRGLTETG LYRISGCDRT VKELKEKFLR VKTVPLLSKV DDIHAICSLL KDFLRNLKEP LLTFRLNRAF MEAAEITDED NSIAAMYQAV GELPQANRDT LAFLMIHLQR VAQSPHTKMD VANLAKVFGP TIVAHAVPNP DPVTMLQDIK RQPKVVERLL SLPLEYWSQF MMVEQENIDP LHVIENSNAF STPQTPDIKV SLLGPVTTPE HQLLKTPSSS SLSQRVRSTL TKNTPRFGSK SKSATNLGRQ GNFFASPMLK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 353-632 of human RGAP1 (NP_001119576.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Alternative Name: RACGAP1

Background: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12.,RACGAP1,CYK4,HsCYK-4,ID-GAP,MgcRacGAP,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Immunology & Inflammation,Cytokines,RACGAP1

Molecular Weight: 71 kDa

Gene ID: 29127

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor