RFC2 antibody (AA 38-297)

Catalog No. ABIN6146879

The Rabbit Polyclonal anti-RFC2 antibody is suitable to detect RFC2 in samples from Human. It has been validated for WB.

Quick Overview for RFC2 antibody (AA 38-297) (ABIN6146879)

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RFC2 Antibody

Binding Specificity: AA 38-297

Sequence: WVEKYRPVKL NEIVGNEDTV SRLEVFAREG NVPNIIIAGP PGTGKTTSIL CLARALLGPA LKDAMLELNA SNDRGIDVVR NKIKMFAQQK VTLPKGRHKI IILDEADSMT DGAQQALRRT MEIYSKTTRF ALACNASDKI IEPIQSRCAV LRYTKLTDAQ ILTRLMNVIE KERVPYTDDG LEAIIFTAQG DMRQALNNLQ STFSGFGFIN SENVFKVCDE PHPLLVKEMI QHCVNANIDE AYKILAHLWH LGYSPEDIIG

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 38-297 of human RFC2 (NP_852136.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RFC2

Target: RFC2 (Replication Factor C (Activator 1) 2, 40kDa (RFC2))

Alternative Name: RFC2

Background: This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.,RFC2,RFC40,Epigenetics & Nuclear Signaling,RFC2

Molecular Weight: 35 kDa/39 kDa

Gene ID: 5982

UniProt: P35250

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA