RHOH antibody (AA 1-191)

Catalog No. ABIN6146942

Product Details anti-RHOH Antibody

Target: RHOH (Ras Homolog Family Member H (RHOH))

Binding Specificity: AA 1-191

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MLSSIKCVLV GDSAVGKTSL LVRFTSETFP EAYKPTVYEN TGVDVFMDGI QISLGLWDTA GNDAFRSIRP LSYQQADVVL MCYSVANHNS FLNLKNKWIG EIRSNLPCTP VLVVATQTDQ REMGPHRASC VNAMEGKKLA QDVRAKGYLE CSALSNRGVQ QVFECAVRTA VNQARRRNRR RLFSINECKI F

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human RHOH (NP_004301.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:10 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RHOH

Target: RHOH (Ras Homolog Family Member H (RHOH))

Alternative Name: RHOH (RHOH Products)

Synonyms: ARHH antibody, TTF antibody, 5830400A04Rik antibody, AU019774 antibody, Arhh antibody, ras homolog family member H antibody, RHOH antibody, Rhoh antibody

Background: The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.,RHOH,ARHH,TTF,Signal Transduction,G protein signaling,Signal Transduction,RHOH

Molecular Weight: 21 kDa

Gene ID: 399

UniProt: Q15669