RHOH antibody (AA 110-190)

Catalog No. ABIN7222226

This Rabbit Polyclonal antibody specifically detects RHOH in WB, ELISA, IF and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RHOH antibody (AA 110-190) (ABIN7222226)

Target: RHOH (Ras Homolog Family Member H (RHOH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-RHOH Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-Rho H Polyclonal Antibody

Specificity: Rho H Polyclonal Antibody detects endogenous levels of Rho H protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Rho H at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RHOH

Target: RHOH (Ras Homolog Family Member H (RHOH))

Alternative Name: Rho H

Background: RHOH, ARHH, TTF, Rho-related GTP-binding protein RhoH, GTP-binding protein TTF, Translocation three four proteinThe protein encoded by RHOH is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. RHOH may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.

Molecular Weight: 21kD

Gene ID: 399

UniProt: Q15669