RIN2 antibody (AA 596-895)

Catalog No. ABIN6146954

This anti-RIN2 antibody is a Rabbit Polyclonal antibody detecting RIN2 in WB. Suitable for Human.

Quick Overview for RIN2 antibody (AA 596-895) (ABIN6146954)

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIN2 Antibody

Binding Specificity: AA 596-895

Sequence: HKCILKPLKG HVEAMLKDFH MADGSWKQLK ENLQLVRQRN PQELGVFAPT PDFVDVEKIK VKFMTMQKMY SPEKKVMLLL RVCKLIYTVM ENNSGRMYGA DDFLPVLTYV IAQCDMLELD TEIEYMMELL DPSLLHGEGG YYLTSAYGAL SLIKNFQEEQ AARLLSSETR DTLRQWHKRR TTNRTIPSVD DFQNYLRVAF QEVNSGCTGK TLLVRPYITT EDVCQICAEK FKVGDPEEYS LFLFVDETWQ QLAEDTYPQK IKAELHSRPQ PHIFHFVYKR IKNDPYGIIF QNGEEDLTTS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 596-895 of human RIN2 (NP_061866.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RIN2

Target: RIN2 (Ras and Rab Interactor 2 (RIN2))

Alternative Name: RIN2

Background: The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants.,RIN2,MACS,RASSF4,Signal Transduction,G protein signaling,Signal Transduction,RIN2

Molecular Weight: 100 kDa/105 kDa

Gene ID: 54453

UniProt: Q8WYP3