Hepcidin antibody (AA 25-85)

Catalog No. ABIN614727

The Mouse Monoclonal anti-Hepcidin antibody (Clone 1F9) (ABIN614727) specifically detects Hepcidin in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for Hepcidin antibody (AA 25-85) (ABIN614727)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Hepcidin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 1F9

Product Details anti-Hepcidin Antibody

Binding Specificity: AA 25-85

Specificity: This antibody reacts to Hepcidin Antimicrobial Peptide (HAMP).

Purification: Protein A Chromatography

Immunogen: Recombinant protein, HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Genename: HAMP

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Alternative Name: Hepcidin / HAMP

Background: Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25 amino acid active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor

Gene ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis