SCN2A antibody (AA 275-401)

Catalog No. ABIN6147435

The Rabbit Polyclonal anti-SCN2A antibody is suitable to detect SCN2A in samples from Human. It has been validated for WB.

Quick Overview for SCN2A antibody (AA 275-401) (ABIN6147435)

Target: SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCN2A Antibody

Binding Specificity: AA 275-401

Sequence: RNKCLQWPPD NSSFEINITS FFNNSLDGNG TTFNRTVSIF NWDEYIEDKS HFYFLEGQND ALLCGNSSDA GQCPEGYICV KAGRNPNYGY TSFDTFSWAF LSLFRLMTQD FWENLYQLTL RAAGKTY

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 275-401 of human SCN2A (NP_001035232.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SCN2A

Target: SCN2A (Sodium Channel, Voltage-Gated, Type II, alpha Subunit (SCN2A))

Alternative Name: SCN2A

Background: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants.,SCN2A,BFIC3,BFIS3,BFNIS,EIEE11,HBA,HBSCI,HBSCII,NAC2,Na(v)1.2,Nav1.2,SCN2A1,SCN2A2,Neuroscience,SCN2A

Molecular Weight: 227 kDa

Gene ID: 6326

UniProt: Q99250