ERCC3 antibody (AA 242-261)

Catalog No. ABIN614756

Product Details anti-ERCC3 Antibody

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Binding Specificity: AA 242-261

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ERCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogen: Synthetic peptide corresponding to aa242-261 of Human ERCC-3.

Clone: 3G4

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.1 M Tris-HCl, pH 7.5.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (Add 40-50% Glycerol) at -20 °C for longer.

Target Details for ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Alternative Name: ERCC3 (ERCC3 Products)

Background: ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kD subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.Synonyms: BTF2-p89, Basic transcription factor 2 89 kDa subunit, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, ERCC-3, TFIIH 89 kDa subunit, TFIIH basal transcription factor complex helicase XPB subunit, XPB, XPBC, Xeroderma pigmentosum group B-complementing protein

Gene ID: 2071

NCBI Accession: NP_000113

UniProt: P19447

Pathways: DNA Damage Repair