SPG7 antibody (AA 1-250)

Catalog No. ABIN6148342

Product Details anti-SPG7 Antibody

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Binding Specificity: AA 1-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MAVLLLLLRA LRRGPGPGPR PLWGPGPAWS PGFPARPGRG RPYMASRPPG DLAEAGGRAL QSLQLRLLTP TFEGINGLLL KQHLVQNPVR LWQLLGGTFY FNTSRLKQKN KEKDKSKGKA PEEDEEERRR RERDDQMYRE RLRTLLVIAV VMSLLNALST SGGSISWNDF VHEMLAKGEV QRVQVVPESD VVEVYLHPGA VVFGRPRLAL MYRMQVANID KFEEKLRAAE DELNIEAKDR IPVSYKRTGF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human SPG7 (NP_003110.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Alternative Name: SPG7 (SPG7 Products)

Synonyms: CAR antibody, CMAR antibody, PGN antibody, SPG5C antibody, AI452278 antibody, AU015315 antibody, Cmar antibody, SPG7, paraplegin matrix AAA peptidase subunit antibody, SPG7 antibody, Spg7 antibody

Background: This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.,SPG7,CAR,CMAR,PGN,SPG5C,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,SPG7

Molecular Weight: 53 kDa/88 kDa

Gene ID: 6687

UniProt: Q9UQ90