SPG7 antibody (AA 71-120)

Catalog No. ABIN7231494

The Rabbit Polyclonal anti-SPG7 antibody (ABIN7231494) specifically detects SPG7 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SPG7 antibody (AA 71-120) (ABIN7231494)

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SPG7 Antibody

Binding Specificity: AA 71-120

Purpose: Rabbit Anti-SPG7 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SPG7 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human SPG7 protein at AA range: 71-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Alternative Name: SPG7

Background: Paraplegin, Cell matrix adhesion regulator, Spastic paraplegia 7 proteinSPG7 encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in SPG7 cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.

Molecular Weight: 87kD

Gene ID: 6687

UniProt: Q9UQ90