TAP1 antibody (AA 524-808)

Catalog No. ABIN6148845

Product Details anti-TAP1 Antibody

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Binding Specificity: AA 524-808

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IYPRVQKAVG SSEKIFEYLD RTPRCPPSGL LTPLHLEGLV QFQDVSFAYP NRPDVLVLQG LTFTLRPGEV TALVGPNGSG KSTVAALLQN LYQPTGGQLL LDGKPLPQYE HRYLHRQVAA VGQEPQVFGR SLQENIAYGL TQKPTMEEIT AAAVKSGAHS FISGLPQGYD TEVDEAGSQL SGGQRQAVAL ARALIRKPCV LILDDATSAL DANSQLQVEQ LLYESPERYS RSVLLITQHL SLVEQADHIL FLEGGAIREG GTHQQLMEKK GCYWAMVQAP ADAPE

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 524-808 of human TAP1 (NP_000584.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TAP1

Target: TAP1 (Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP1))

Alternative Name: TAP1 (TAP1 Products)

Synonyms: ABC17 antibody, ABCB2 antibody, APT1 antibody, D6S114E antibody, PSF-1 antibody, PSF1 antibody, RING4 antibody, TAP1*0102N antibody, TAP1N antibody, abc17 antibody, abcb2 antibody, apt1 antibody, psf1 antibody, ring4 antibody, tap1a antibody, tap1n antibody, Abcb2 antibody, Ham-1 antibody, Ham1 antibody, MTP1 antibody, TAP antibody, Tap-1 antibody, Y3 antibody, Cim antibody, transporter 1, ATP binding cassette subfamily B member antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) L homeolog antibody, transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP1 antibody, tap1.L antibody, Tap1 antibody

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene.,TAP1,ABC17,ABCB2,APT1,D6S114E,PSF-1,PSF1,RING4,TAP1*0102N,TAP1N,Signal Transduction,TAP1

Molecular Weight: 87 kDa

Gene ID: 6890

UniProt: Q03518

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process