TXN antibody (C-Term)

Catalog No. ABIN6149720

The Rabbit Polyclonal anti-TXN antibody has been validated for WB, IHC, IP and IF. It is suitable to detect TXN in samples from Human. There is 1 publication available.

Quick Overview for TXN antibody (C-Term) (ABIN6149720)

Target: TXN (Thioredoxin (TXN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-TXN Antibody

Binding Specificity: C-Term

Sequence: DKLVVVDFSA TWCGPCKMIK PFFHSLSEKY SNVIFLEVDV DDCQDVASEC EVKCMPTFQF FKKGQKVGEF SGANKEKLEA TINELV

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 20 to the C-terminus of human Thioredoxin 1 (Trx1/Thioredoxin 1 (Trx1/TXN)) (NP_003320.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TXN antibody (ABIN6149720)

Li, Zhang, Zhang, Lü, Miao, Yang, Huang, Ma, Han, Deng, Fan, Liu, Huo, Xu, Chen, Wang, Feng: "GSNOR modulates hyperhomocysteinemia-induced T cell activation and atherosclerosis by switching Akt S-nitrosylation to phosphorylation." in: Redox biology, Vol. 17, pp. 386-399, (2018) (PubMed).

Target Details for TXN

Target: TXN (Thioredoxin (TXN))

Alternative Name: TXN

Background: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.,TXN,TRDX,TRX,TRX1,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Endocrine & Metabolism,TXN

Molecular Weight: 9 kDa/11 kDa

Gene ID: 7295

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis