APOA2 antibody
Quick Overview for APOA2 antibody (ABIN614994)
Target
See all APOA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody specifically binds to human Apo AII.
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Purification
- Affinity chromatography
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Immunogen
- Human Apo AII Genename: APOA2
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 75 mM PBS, 75 mM sodium chloride, pH 7.2, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer (add 0-50% glycerol).
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- APOA2 (Apolipoprotein A-II (APOA2))
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Alternative Name
- Apolipoprotein A II (Apo AII)
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Background
- Apolipoprotein (Apo-) A-II is the second most abundant protein of the high density lipoprotein particles. The apo-A-II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre-peptide, a short N-terminal domain and a C-terminal domain composed of a variable number of lipid-binding amphipathic helices. Familial apo-A-II deficiency may result from a splice-junction alteration which blocks splicing of intron 3 from the primary transcript and result the formation of a non-functional mRNA.Synonyms: APOA2, Apo-AII, ApoA-II, Apolipoprotein A-II, Apolipoprotein A2
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Gene ID
- 336
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NCBI Accession
- NP_001634
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UniProt
- P02652
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity, Lipid Metabolism
Target
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