ACTN3 antibody (N-Term)

Catalog No. ABIN615863

Product Details anti-ACTN3 Antibody

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to the N-term of Alpha-actinin 3, Skeletal Muscle Isoform (ACTN3).

Purification: Immunoaffinity Chromatography

Immunogen: ACTN3 antibody was raised against synthetic peptide - KLH conjugated Genename: ACTN3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for ACTN3

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Alternative Name: alpha-Actinin-3 / ACTN3 (ACTN3 Products)

Synonyms: CG8953 antibody, Dmel\\CG8953 antibody, ORF1 antibody, acta-3 antibody, dabp antibody, ACTN2 antibody, actn3 antibody, actnl antibody, zgc:63559 antibody, fb95c03 antibody, wu:fb95c03 antibody, wu:fc11d03 antibody, zgc:77243 antibody, actinin alpha 3 (gene/pseudogene) antibody, actinin alpha 3 antibody, alpha actinin 3 antibody, actinin alpha 3a antibody, actinin alpha 3 (gene/pseudogene) L homeolog antibody, alpha-actinin-3 antibody, actinin alpha 3b antibody, ACTN3 antibody, Actn3 antibody, actn3a antibody, actn3.L antibody, actn3 antibody, LOC100439754 antibody, actn3b antibody

Background: Alpha-actinin is an actin-binding protein with multiple roles in different cell types. ACTN3 expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments.Synonyms: Alpha actinin skeletal muscle isoform 3, F-actin cross-linking protein

Gene ID: 89

NCBI Accession: NP_001095

UniProt: Q08043

Pathways: Cell-Cell Junction Organization