Fibrillarin antibody
(1 reference)-
- Target See all Fibrillarin (FBL) Antibodies
- Fibrillarin (FBL)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Fibrillarin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human FBL
- Isotype
- IgG
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anti-Fibrillarin (FBL) antibody
FBL Reactivity: Human WB, IF, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) (AA 100-321) antibodyFBL Reactivity: Human WB, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL Reactivity: Saccharomyces cerevisiae WB, IF Host: Mouse Monoclonal 38F3 unconjugated
anti-Fibrillarin (FBL) (AA 1-321) antibodyFBL Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 4G9-E4 unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) (Internal Region) antibodyFBL Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) (AA 61-110) antibodyFBL Reactivity: Human, Mouse, Rat, Dog, Cow, Monkey, Horse, Guinea Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) (N-Term) antibodyFBL Reactivity: Human, Mouse, Rat, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Fibrillarin (FBL) antibodyFBL Reactivity: Saccharomyces cerevisiae WB, IHC, IF, ICC Host: Mouse Monoclonal 38F3 unconjugated
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- Application Notes
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C/-80 °C
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: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
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: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
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- Target
- Fibrillarin (FBL)
- Alternative Name
- FBL (FBL Products)
- Background
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Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
Synonyms: FBL, FIB, FLRN, RNU3IP1 - Gene ID
- 2091
- UniProt
- P22087
- Pathways
- Ribonucleoside Biosynthetic Process
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