Tissue factor antibody (PE)
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- Target See all Tissue factor (F3) Antibodies
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Tissue factor antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The mouse monoclonal antibody HTF-1, also known as HTF1-7B8, recognizes an extracellular epitope of CD142 (tissue factor, coagulation factor III), a type I glycoprotein expressed on endothelial cells, monocytes, macrophages, and platelets upon induction by inflammatory mediators, and expressed constitutively by some tumors, the vasculature, placenta, kidney, and central nervous system.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Human brain tissue factor (CD142)
- Clone
- HTF-1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product F3 Primary Antibody
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- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Comment
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
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- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- Target
- Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))
- Alternative Name
- CD142 (F3 Products)
- Synonyms
- CD142 antibody, TF antibody, TFA antibody, PRO1557 antibody, PRO2086 antibody, TFQTL1 antibody, f3 antibody, AA409063 antibody, Cf-3 antibody, Cf3 antibody, tf antibody, zgc:112151 antibody, coagulation factor III, tissue factor antibody, transferrin antibody, coagulation factor IIIa antibody, coagulation factor III antibody, tissue factor antibody, coagulation factor IIIb antibody, coagulation factor III (thromboplastin, tissue factor) S homeolog antibody, F3 antibody, TF antibody, f3a antibody, tf antibody, f3b antibody, f3.S antibody
- Background
- Coagulation factor III, tissue factor,CD142, also known as coagulation factor III, tissue thromboplastin, and tissue factor. It is a transmembrane glycoprotein, which enables cells to initiate the blood coagulation cascades, and functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. It is the only one factor in the coagulation pathway for which a congenital deficiency has not been described.,F3, tissue factor, tissue thromboplastin, coagulation factor III, TF, TFA
- Gene ID
- 2152
- UniProt
- P13726
- Pathways
- Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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