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H2AFX antibody (pSer139)

Name: H2AFX antibody (pSer139)
SKU: ABIN6241012
Availability: InStock

The Mouse Monoclonal anti-H2AFX antibody (ABIN6241012) specifically detects H2AFX in WB and ICC. The antibody is reactive with Human and Mouse samples.

Western blot detection of Phosphorylation of H2A. (H2AFX antibody (pSer139))

Immunofluorescent analysis of Phosphorylation of H2A. (H2AFX antibody (pSer139))

ICC

2 images

Catalog No. ABIN6241012

$451.00

Plus shipping costs $50.00

100 μL

Shipping to: United States

Delivery in 10 to 12 Business Days

Quick Overview for H2AFX antibody (pSer139) (ABIN6241012)

Target

See all H2AFX Antibodies

H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity

Human, Mouse

Host

Mouse

Clonality

Monoclonal

Conjugate

This H2AFX antibody is un-conjugated

Application

Western Blotting (WB), Immunocytochemistry (ICC)

Discover our top product H2AFX Primary Antibody

Binding Specificity
42

21

18

10

5

5

5

5

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer139

Immunogen

Recombinant Protein
anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 938CT5-1-1 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (H2AXS139ph) antibody
H2AFX Reactivity: Human WB, ELISA, IF, ChIP Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibody
H2AFX Reactivity: Human, Mouse, Rat WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibody
H2AFX Reactivity: Human WB, ELISA, ICC, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) antibody
H2AFX Reactivity: Human WB, ICC, FACS Host: Rabbit Monoclonal 23GB6040 unconjugated Recombinant Antibody

anti-H2A Histone Family, Member X (H2AFX) (H2A.XS139ph) antibody
H2AFX Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 980CT1-5-5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) antibody
H2AFX Reactivity: Human WB, IHC (p) Host: Mouse Monoclonal 8C5 unconjugated

anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibody
H2AFX Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated

anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibody
H2AFX Reactivity: Human WB, IF, ICC, ChIP Host: Rabbit Polyclonal unconjugated

Application Notes

WB: 1:2000. ICC: 1:400

Restrictions

For Research Use only
Format

Liquid

Storage

4 °C,-20 °C
Target

H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name

Histone H2A.X

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.

UniProt

P16104

Pathways

Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus