WDR77 antibody

Catalog No. ABIN6241347

The Mouse Monoclonal anti-WDR77 antibody is suitable to detect WDR77 in samples from Human and Mouse. It has been validated for WB and ICC.

Quick Overview for WDR77 antibody (ABIN6241347)

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This WDR77 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-WDR77 Antibody

Immunogen: Recombinant Protein

Application Details

Application Notes: WB: 1:1000. ICC: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Target Details for WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Alternative Name: WDR77

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization